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Clinical Trial

Task and Physiological Specific Stimulation for Recovery of Autonomic Function, Voluntary Movement, and Standing Using Epidural Stimulation and Training After Severe Spinal Cord Injury

ClinicalTrials.gov11/8/2017ยท11/08/17๐ŸŒ USA

Summary

This trial evaluates task and physiological specific stimulation for recovery of autonomic function after spinal cord injury. The study delivers targeted transcutaneous spinal cord stimulation during specific physiological challenges to restore cardiovascular, bladder, and bowel function.

Why it matters

Autonomic dysfunction is a major cause of morbidity and mortality after SCI. This approach of pairing stimulation with specific physiological tasks represents a novel closed-loop neuromodulation strategy that could restore multiple autonomic functions simultaneously.

#Phase 2#Spinal Cord Injury#Neurostimulation#Spinal Cord Stimulation#Non-invasive#Bioelectronic Medicine#Closed-Loop#USA

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