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Clinical Trial

Transdiagnostic Circuit Mapping of Prefrontal Targets in Accelerated Transcranial Magnetic Stimulation

ClinicalTrials.gov1/30/2025ยท01/30/25๐ŸŒ USA

Summary

This Phase 2 trial maps prefrontal circuit targets for accelerated transcranial magnetic stimulation across psychiatric conditions including obsessive-compulsive disorder, major depression, and schizophrenia. Using functional connectivity MRI, the study identifies personalized TMS targets to optimize treatment response.

Why it matters

Current TMS for OCD uses standardized targets with variable efficacy. This transdiagnostic circuit mapping approach could identify optimal stimulation sites tailored to each patient's unique neural circuitry, representing a major advance toward precision neuromodulation for psychiatric disorders.

#Phase 2#OCD#Neurostimulation#TMS#Non-invasive#Neuroimaging#Neurodiagnostics#USA

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