Brain computer interface training with motor imagery and functional electrical stimulation for patients with severe upper limb paresis after stroke: a randomized controlled pilot trial
Summary
This RCT examined BCI training combining motor imagery with FES for severe upper limb paresis in subacute stroke. While more patients in the BCI group improved relative to group size, the difference was not statistically significant. Preserved corticospinal tract integrity, measured by TMS, was a much stronger predictor of motor improvement than intervention type.
Why it matters
This is the first RCT examining BCI training exclusively in subacute stroke patients with severe paresis. The finding that corticospinal tract integrity predicts recovery better than intervention type highlights the importance of patient selection for BCI rehabilitation. Future studies should stratify by CST integrity to better identify who benefits most from BCI-FES training.
Want the full NeurotechMag Pro intelligence database?
Access 800+ papers, trials, patents, funding rounds and news items — updated daily.
Start free trial