Graphene cortical interface demonstrates superior signal fidelity to metal electrodes in human intraoperative study
Summary
INBRAIN Neuroelectronics and University of Manchester researchers report data from the first eight patients implanted with graphene cortical interfaces during brain tumor resection (NCT06368310). The ultra-thin, flexible graphene electrodes captured neural signals at resolution and fidelity that conventional metal electrodes 'can barely see' according to co-founder Kostas Kostarelos. In awake surgery cases, the interface enabled high-resolution decoding of speech representation in the brain during object-naming tasks. Zero perioperative device failures were observed. Full results are expected following the 90-day follow-up phase.
Why it matters
First human data from graphene neural interfaces showing superior signal quality to metal electrodes in actual patients — not just in vitro or animal models — is the translational milestone the graphene BCI field has been building toward since Andre Geim and Kostya Novoselov won the 2010 Nobel Prize for graphene. This data establishes graphene as a viable clinical neural interface material, opening the door to INBRAIN's planned BCI-Tx therapeutic applications.
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