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Research Paper

Decoding naturalistic speech from cortical surface recordings with sequence-to-sequence models

PubMed4/9/2026ยท04/09/26๐ŸŒ USA

Summary

UCSF researchers decoded natural conversational speech from electrocorticography (ECoG) recordings using a sequence-to-sequence deep learning architecture. Decoding of 40 participants' ECoG during open-set speech production achieved median word error rates of 9.1%, approaching commercially viable performance for speech BCIs.

Why it matters

Open-set natural speech decoding from ECoG at sub-10% word error rate crosses a critical commercial viability threshold. This performance level could support practical clinical deployment for ALS and locked-in syndrome patients.

#ALS#BCI#Bioelectronic Medicine#Neurostimulation

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