Clinical Trial
Intracranial Investigation of Neural Circuity Underlying Human Mood
ClinicalTrials.gov7/3/2023·07/03/23🌐 USA
Summary
This trial uses intracranial electrophysiology to investigate neural circuitry underlying human mood and emotional processing in epilepsy patients with implanted deep brain stimulation electrodes. The study records directly from limbic structures to understand how electrical stimulation modulates mood circuits and could inform treatment-resistant depression therapies.
Why it matters
Direct human brain recordings during natural emotional experiences are extremely rare. This research bridges critical gaps in understanding how neuromodulation affects mood circuits, with implications for both epilepsy comorbidities and psychiatric device development.
#Phase 2#Epilepsy#Mental Health Tech#Neural Recording#Deep Brain Stimulation#Neuroimaging#USA
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