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Funding Round

Sinaptica Therapeutics secures €18M Series A for personalized TMS Alzheimer's therapy

Fierce Biotech3/27/2026·03/27/26🌐 Europe

Summary

Genoa-based Sinaptica Therapeutics raised €18M Series A led by Sofinnova Partners, with Eureka Capital Partners and CDP Venture Capital. Sinaptica's personalized TMS protocol, guided by individual connectome mapping from fMRI, showed 35% reduction in cognitive decline versus standard TMS in a 65-patient Phase 2 trial recently published in Brain.

Why it matters

The connectome-guided personalization approach is backed by Stanford's pioneering SCC DBS work. Sinaptica translating this principle to non-invasive TMS for Alzheimer's represents a premium precision medicine opportunity in a market desperate for effective interventions.

#TMS#Alzheimers#Closed-Loop#Neuroimaging#Europe

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