Methods and systems for optimizing therapy using stimulation mimicking natural seizures
Summary
NeuroPace 2025-granted patent covering optimization of RNS System therapy by delivering stimulation patterns that mimic the electrographic signature of the patient's own natural seizures — using the seizure waveform as a personalized template to identify the most effective parameters for aborting future seizures. Machine learning identifies stimulation patterns optimally matched to each patient's specific epileptiform circuit dynamics.
Why it matters
Granted 2025, US12303694 is NeuroPace's next-generation AI therapy optimization approach — using each patient's own seizure waveform as a personalized stimulation template. This is the scientific basis for the progressive efficacy improvement in long-term RNS data, and the methodology powering the Nautilus next-generation RNS System in development.
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