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Research Paper

Parametric optimization of transcranial focused ultrasound neuromodulation of the periaqueductal grey for blood pressure reduction

Brain Stimulation6/22/2026ยท06/22/26๐ŸŒ USA

Summary

This study optimized parameters for transcranial focused ultrasound neuromodulation targeting the periaqueductal gray for blood pressure control in resistant hypertension. The research identified optimal stimulation parameters for achieving clinically meaningful blood pressure reduction.

Why it matters

With 10-20% of hypertension patients resistant to pharmacological treatment, non-invasive neuromodulation offers a promising alternative. This parametric optimization provides the foundation for designing larger clinical trials of FUS for cardiovascular neuromodulation.

#Focused Ultrasound#Neurostimulation#Non-invasive#Neuroimaging

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