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Funding Round

Sinaptica Therapeutics raises €8M seed extension for personalized Alzheimer's TMS Phase 2

Sofinnova Partners4/5/2026·04/05/26🌐 Europe

Summary

Italian TMS startup Sinaptica Therapeutics secured an €8M extension from Sofinnova Partners ahead of their planned Phase 2 trial of connectome-guided personalized TMS for Alzheimer's disease. The extension bridges to Phase 2 initiation and funds manufacturing scale-up of their individualized neuronavigation-integrated TMS protocol delivery system.

Why it matters

Sofinnova doubling down with an extension before Phase 2 initiation signals high confidence in Sinaptica's approach. The connectome-guided TMS concept has strong scientific backing from the Stanford SCC DBS literature and represents a genuinely differentiated Alzheimer's non-invasive neuromodulation strategy.

#Alzheimers#Neuroimaging#Phase 2#TMS

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