Clinical Trial
Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder
ClinicalTrials.gov1/1/2022·01/01/22🌐 USA
Summary
This study at Mount Sinai uses connectomic imaging to guide selective stimulation of anterior limb of internal capsule pathways for treatment-resistant OCD. Rather than uniform stimulation, the approach uses patient-specific brain connectivity mapping to focally stimulate specific white matter pathways.
Why it matters
Connectomic DBS represents a paradigm shift from anatomical targeting to personalized network-based neuromodulation. For OCD, this could dramatically improve patient selection and outcomes by ensuring stimulation is delivered to the exact pathways mediating each patient's symptoms.
#Deep Brain Stimulation#OCD#Neurostimulation#Closed-Loop#Phase 2#USA#Neuroimaging
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