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Research Paper

Spike-based neural codes carry 10x more information than rate codes in human motor cortex

PubMed4/17/2026ยท04/17/26๐ŸŒ USA

Summary

Analysis of Utah Array recordings from 4 BrainGate participants during attempted hand movement found that precise spike timing patterns (with 1ms resolution) encoded 10.3x more information about intended movement direction and force than firing rate alone. A spike-timing-aware decoder reduced cursor control error rates by 67% versus rate-based decoding.

Why it matters

Most clinical BCIs use firing rate decoding โ€” the simplest but least information-rich neural code. This result showing 10x more information in spike timing patterns motivates a fundamental shift in BCI decoder design that could dramatically improve performance without adding more electrodes.

#BCI#Neural Interfaces#Neuroimaging#Neurostimulation

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