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Israel's WeissBio raises $35M for antibody-based targeted drug delivery across the blood-brain barrier

Calcalist Tech4/20/2026ยท04/20/26๐ŸŒ Europe

Summary

Tel Aviv-based WeissBio closed a $35M Series A for their proprietary transferrin receptor-targeting antibody platform that ferries therapeutic payloads across the blood-brain barrier. Initial indications target glioblastoma and Alzheimer's disease. Their lead conjugate shows 15x higher brain penetration than free drug in preclinical models.

Why it matters

The blood-brain barrier remains the primary obstacle to CNS drug delivery. A 15x penetration improvement in preclinical models, if it holds in humans, could revive numerous CNS drug candidates previously abandoned due to poor brain exposure.

#Alzheimers#Industry#Israel#Venture Capital

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