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Research Paper

Interventional Psychiatry and Emerging Treatments for Posttraumatic Stress Disorder: A Systematic Review

Psychiatry and Clinical Psychopharmacology11/8/2025ยท11/08/25๐ŸŒ Europe

Summary

This systematic review evaluated 94 studies on interventional treatments for PTSD including 39 on TMS, 8 on IV ketamine, and 14 on MDMA-assisted therapy. RCTs demonstrated response rates of 12.5% to 80% for TMS and 50% to 87% for MDMA-assisted therapy. Most treatments were well tolerated with mild transient adverse effects.

Why it matters

PTSD affects millions and conventional treatments fail many patients. This review positions neuromodulation as a key component of interventional psychiatry, supporting expanded access to TMS and other emerging treatments for this debilitating condition.

#TMS#PTSD#Mental Health Tech#Neurostimulation#Non-invasive#Research Tools

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