Clinical Trial
Enabling Forelimb Function With Agonist Drug and Epidural Stimulation in SCI
ClinicalTrials.gov7/1/2013·07/01/13🌐 USA
Summary
This Phase 1/Phase 2 trial evaluates epidural spinal cord stimulation combined with the drug buspirone to enable forelimb function in individuals with chronic cervical spinal cord injury and tetraplegia. The study tests whether the combination of targeted electrical stimulation and a serotonin receptor agonist can activate previously paralyzed upper limb muscles.
Why it matters
This innovative combination of an implanted neurostimulation device with pharmacological enhancement could provide a new therapeutic pathway for upper limb recovery in tetraplegia, addressing one of the most debilitating consequences of cervical spinal cord injury.
#Phase 2#Spinal Cord Injury#Neurostimulation#Neuroprosthetics#Spinal Cord Stimulation#Neuropharmacology#USA
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