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Salvia BioElectronics raises $60M Series B to complete migraine implant clinical program

Salvia BioElectronics9/15/2025ยท09/15/25๐ŸŒ Europe

Summary

Eindhoven-based Salvia BioElectronics raised $60M in a Series B to complete clinical development and prepare commercial launch of their implantable closed-loop neurostimulation device for drug-resistant chronic migraine. The device detects cortical spreading depolarization biomarkers โ€” the neural signature of migraine attacks โ€” and delivers preemptive stimulation to abort attacks before they become symptomatic. This is Salvia's largest funding round and brings total raised to over $100M.

Why it matters

Salvia's $60M Series B positions them as the best-funded migraine implant company globally. The closed-loop detection-and-abort approach is mechanistically superior to blind prophylactic stimulation and, if it works, could be the first treatment that actually prevents migraines rather than treating them after onset.

#Bioelectronic Medicine#Chronic Pain#Closed-Loop#Europe#Industry#Neurostimulation#Venture Capital

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