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Salvia BioElectronics raises $60M Series B to commercialize VNS implant for chronic migraine

New Market Pitch11/1/2025ยท11/01/25๐ŸŒ Europe

Summary

Salvia BioElectronics raised $60 million in a Series B to finish clinical development and prepare for commercial launch of their SALVIA implantable vagus nerve stimulation system for chronic migraine. The Netherlands-based company's device targets the cervical vagus nerve to prevent migraine attacks in high-frequency and chronic migraine patients who have failed multiple preventive medications. Migraine affects 1 billion people globally and is the leading cause of disability in adults under 50 โ€” yet current device-based options are limited to CGRP antibody biologics and a single FDA-cleared VNS device (gammaCore). Salvia's implantable approach targets patients with the most severe, treatment-resistant migraine burden.

Why it matters

A $60M Series B for implantable VNS migraine prevention is the largest single round ever raised for a device-based migraine prevention company. Salvia's clinical program is specifically targeting the chronic migraine patients who have failed CGRP antibodies โ€” the treatment-resistant tail of the migraine population where pharmacological options are exhausted. An implantable VNS that prevents rather than aborts migraines would be transformative for this population.

#Bioelectronic Medicine#Chronic Pain#Europe#Industry#Neurostimulation#Venture Capital

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