Research Paper
Control Signals in Closed-Loop Spinal Cord Stimulation in Patients with Chronic Pain: A Scoping Review
Neuromodulation1/8/2026·01/08/26🌐 USA
Summary
This scoping review evaluated 28 articles on closed-loop spinal cord stimulation systems for chronic pain, examining control signals including subjective pain ratings, position and movement data, and evoked compound action potentials. The review found that no existing model fully integrates both subjective patient reports with objective neural biomarkers.
Why it matters
The review highlights a critical gap in closed-loop SCS: the lack of algorithms that combine subjective pain experience with objective neural signals. This insight could guide development of more personalized, adaptive pain therapies that respond to the full patient experience.
#Closed-Loop#Spinal Cord Stimulation#Chronic Pain#AI#Neurostimulation
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