Research Paper
Colorimetric sensing for transdermal phospho-Tau 181 detection mediated by wearable microneedle functionalized with gold nanoparticle (MN-AuNP)
Talanta1/1/2026·01/01/26🌐 Europe
Summary
Researchers developed a wearable microneedle immunosensor functionalized with gold nanoparticles for transdermal detection of p-Tau181, a key Alzheimer's biomarker. The 3D microneedle architecture achieved a detection limit of 16 pg/mL, a 30-fold improvement over 2D surfaces, enabling instrument-free colorimetric readout.
Why it matters
This non-invasive, low-cost diagnostic platform could enable routine point-of-care screening for Alzheimer's disease through interstitial fluid biomarker detection. The wearable format makes repeated longitudinal monitoring feasible, potentially enabling earlier detection and treatment initiation.
#Neurodiagnostics#Wearables#Biomarkers#Alzheimers#EEG
Want the full NeurotechMag Pro intelligence database?
Access 800+ papers, trials, patents, funding rounds and news items — updated daily.
Start free trialAlready a member? Sign in