Synergistic Potential of Non-invasive Brain and Spinal Cord Stimulation for Improving Sensorimotor and Cognitive Functions After Neurological Injury
Summary
This Phase 2 trial investigates the synergistic effects of combining transcranial direct current stimulation (tDCS) with transcutaneous spinal cord stimulation (tSCS) in participants with cervical spinal cord injury and stroke. The study evaluates whether simultaneous non-invasive brain and spinal cord stimulation during cognitive-motor tasks enhances upper limb sensorimotor and cognitive function recovery more than either intervention alone.
Why it matters
This is the first study to systematically test combined brain-spine neuromodulation in both SCI and stroke populations. If the synergistic approach proves effective, it could establish a new rehabilitation paradigm that accelerates recovery without requiring invasive surgery.
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