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Patent Filing

Seizure sensing and detection using an implantable device

NeuroPace Inc10/26/2004ยท10/26/04๐ŸŒ USA

Summary

NeuroPace's foundational patent covering the core architecture of the RNS System: an implantable device that continuously records intracranial EEG via electrodes placed at the seizure focus, applies detection algorithms to identify epileptiform activity, and automatically delivers brief bursts of electrical stimulation to normalize brain activity and abort seizures before they fully develop. The patent covers the closed-loop sensing, detection, and response cycle that defines responsive neurostimulation โ€” a fundamentally different paradigm from open-loop DBS or VNS that stimulate on a fixed schedule regardless of brain state.

Why it matters

This is the foundational patent on which every closed-loop brain-responsive neurostimulation system is built. Filed in 2002 and granted in 2004, US6810285 established the intellectual property foundation for the RNS System's FDA approval in 2013 and its 82% median seizure reduction at 3-year post-approval study. It covers the Depth Lead, Cortical Strip Lead, and RNS Neurostimulator as listed on NeuroPace's official statutory patent marking page.

#Epilepsy#Closed-Loop#Neurostimulation#Neural Interfaces#USA

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