Neurotech Clinical Trials — Free Preview
Registered clinical trials across neurotechnology, with a short preview of scope and status for each study. Showing the 24 most recent of 100 tracked.
Latest clinical trials
- ClinicalTrials.govApr 21, 2026
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
The long-running BrainGate2 multi-site feasibility study continues enrolling ALS, brainstem stroke, and SCI patients at 5 US academic centers. Participants receive implanted Utah Array BCIs and participate in sessions using neural signals to control computers.
Read the preview - ClinicalTrials.govApr 20, 2026
FIH Clinical Investigation of Graphene Electrodes for Brain Mapping
The completed enrollment phase of INBRAIN Neuroelectronics' first-in-human study of their graphene cortical interface at Salford Royal Hospital, Manchester. Ten patients recruited, eight surgically treated during brain tumor resection procedures with no…
Read the preview - ClinicalTrials.govApr 18, 2026
OVERTURE Phase 3: Gamma Sensory Stimulation for Alzheimer's Disease (NCT05637801)
Phase 3 trial of Cognito Therapeutics' Spectris wearable (40Hz gamma light and sound, 1 hour/day) in 550 early Alzheimer's patients over 18 months. Primary endpoint: CDR-SB cognitive score change.
Read the preview - ClinicalTrials.govApr 1, 2026
SONIC: Subcallosal Cingulate DBS for Treatment-Resistant Depression (NCT03437928)
Multicenter trial of subcallosal cingulate white matter DBS in 60 severely treatment-resistant depression patients across 6 US sites, using diffusion tractography-guided targeting to identify the optimal stimulation site per individual. Extends Emory's…
Read the preview - ClinicalTrials.govMar 31, 2026
Connect-One: Early Feasibility Study of Connexus Brain-Computer Interface (BCI) to Provide Human Connection Through Communication
The Connect-One Study is Paradromics' early feasibility study of the Connexus Brain-Computer Interface for patients with impaired communication due to ALS, stroke, or other neuromuscular diseases. The Connexus BCI is a high-data-rate cortical implant…
Read the preview - ClinicalTrials.govMar 17, 2026
Implantable Brain-Computer Interface for Upper-Limb Recovery After Stroke
) is suitable for a six-month intensive rehabilitation program using Brain-Machine Interface. * A second phase, consisting of implementing the intensive rehabilitation program, first in the traditional manner, without the Brain-Machine Interface (2 to 5…
Read the preview - ClinicalTrials.govJan 1, 2026
Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)
The INTENT study evaluates a high-bandwidth neural interface system developed by Johns Hopkins University for individuals with tetraplegia, ALS, and other neuromuscular disorders. The system aims to enable direct brain control of external devices including…
Read the preview - ClinicalTrials.govDec 15, 2025
Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury
This study evaluates passive neurosensory reintegration training as a tool to augment mild traumatic brain injury recovery. The non-invasive neuromodulation device delivers specific patterns of sensory stimulation designed to promote neural reorganization…
Read the preview - ClinicalTrials.govDec 11, 2025
Empower: tDCS for Major Depressive Disorder at Home — Phase 2 RCT (NCT05202119) — Completed, FDA PMA approved
Flow Neuroscience's completed Phase 2 RCT (NCT05202119) that formed the basis for the December 11, 2025 FDA PMA approval of FL-100. The double-blind, placebo-controlled, randomized superiority trial evaluated at-home tDCS (2mA, 30 min/day, 3-5x/week, 10…
Read the preview - ClinicalTrials.govDec 2, 2025
Clinical Effects of Low-Intensity Focused Ultrasound Neuromodulation in Patients With Neurological and Psychiatric Disorders
This trial investigates the clinical effects of low-intensity focused ultrasound neuromodulation in patients with Parkinson's disease, essential tremor, dystonia, and epilepsy who are candidates for deep brain stimulation surgery. The study uses…
Read the preview - ClinicalTrials.govDec 1, 2025
Functional Outcomes and Control Using Synchron BCI - Australia
This study evaluates the Synchron Stentrode, an endovascular brain-computer interface that is implanted via the jugular vein rather than through open brain surgery. Participants with motor neurone disease (ALS) in Australia will be implanted with the…
Read the preview - ClinicalTrials.govNov 28, 2025
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial
This Phase 2/Phase 3 multicenter randomized controlled trial evaluates high-definition transcranial direct current stimulation (HD-tDCS) in patients with amyotrophic lateral sclerosis. The study delivers targeted non-invasive brain stimulation to the…
Read the preview - ClinicalTrials.govNov 24, 2025
Targeted Accelerated TMS for Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a highly prevalent and debilitating condition among veterans and active-duty military personnel, with rates as high as 30% in certain combat-exposed populations. Conventional treatments such as prolonged exposure…
Read the preview - ClinicalTrials.govNov 14, 2025
Home-Based Transcranial Direct Current Stimulation in Major Depressive Disorder: a Multi-Centre, Two-Parallel Group, Superiority Randomised Controlled Trial
Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies.
Read the preview - ClinicalTrials.govNov 12, 2025
A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Transcranial Magnetic Stimulation for Treatment Resistant Depression: The MIND1 Trial
Major depressive disorder (MDD) is a significant public health problem and leading cause of worldwide disability. Treatment resistance is common in MDD, however, for these individuals, targeted noninvasive brain stimulation is an alternative.
Read the preview - ClinicalTrials.govNov 10, 2025
Accelerated High-Dose tDCS for Depression: An Open-Label Outpatient Pilot Study
In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain…
Read the preview - ClinicalTrials.govNov 1, 2025
BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities (BCI@home)
This study evaluates the use of brain-computer interfaces (BCI) at home for children ages 5-18 with severe physical disabilities including cerebral palsy and pediatric stroke. Participants receive a BCI kit with headset and software, then complete 12…
Read the preview - ClinicalTrials.govNov 1, 2025
Neuronavigated Transcranial Magnetic Stimulation As An Adjunctive Treatment For Chronic Tinnitus
This trial evaluates neuronavigated repetitive transcranial magnetic stimulation as an adjunctive treatment for chronic tinnitus. Using MRI-guided neuronavigation, the study precisely targets the auditory cortex with low-frequency rTMS to suppress…
Read the preview - ClinicalTrials.govOct 20, 2025
Restoration of Central Vision With the PRIMA System in Patients With Atrophic Age-Related Macular Degeneration
The PRIMAvera pivotal clinical trial of Science Corporation's PRIMA retinal BCI implant in 38 patients with geographic atrophy (advanced dry AMD) — the study whose results were published in NEJM October 2025 showing 80% of patients restored functional…
Read the preview - ClinicalTrials.govOct 17, 2025
ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury
This study evaluates the ARC-IM implantable spinal cord stimulation system for managing symptomatic blood pressure instability secondary to spinal cord injury. The device delivers targeted epidural electrical stimulation to restore autonomic cardiovascular…
Read the preview - ClinicalTrials.govOct 14, 2025
Intracranial Recording and Stimulation of the Human Hippocampal-Amygdala Circuit During Virtual Reality Fear Conditioning
The goal of this clinical trial is to learn how people respond to fear-related experiences in a virtual reality (VR) environment. The study will also look at how brain activity and body responses are connected to learning and memory of fear.
Read the preview - ClinicalTrials.govOct 1, 2025
Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep
This study evaluates whether repetitive transcranial magnetic stimulation (rTMS) targeting the default mode network can improve sleep quality in adults with chronic insomnia. Participants will receive either active rTMS or sham stimulation over 10 sessions…
Read the preview - ClinicalTrials.govSep 1, 2025
Control of Assistive Devices Via Brain-Computer Interface Technology
This Neuralink-sponsored study evaluates the use of the N1 brain-computer interface implant to enable participants with tetraplegia or ALS to control an assistive robotic arm. Building on the PRIME study, this trial specifically tests BCI-driven control of…
Read the preview - ClinicalTrials.govAug 1, 2025
Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease
This trial evaluates a combined non-invasive brain stimulation and exercise intervention for patients with amyotrophic lateral sclerosis. The study integrates repetitive transcranial magnetic stimulation with structured physical exercise to assess…
Read the preview
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